Invitrogen™ VNN3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534459

Product Code. 15305391

Description

A suggested positive control is human brain tissue lysate. PA5-34459 can be used with blocking peptide PEP-1501.

The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.

Specifications

• Antigen: VNN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VNN3
• Gene Alias: HSA238982; pantetheinase pseudogene; pantetheinase-associated gene expressed in leukocytes (PAGEL)-alpha; RGD1560609; vanin 1 pseudogene; vanin 3; vanin-3; Vascular non-inflammatory molecule 3; VNN3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26464, 498992, 55350
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8WZ42, Q9QZ25
• Gene Symbols: VNN3
• Immunogen: A 19 amino acid synthetic peptide near the carboxy terminus of human VNN3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG