VMP1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA556555

Product Code. 15794461

Description

Immunogen sequence: LYLGPHIASV TLAAYECNSV NFPEPPYPDQ IICPDEEGTE GTISLWSIIS KVRIEACMWG IGTAIGELPP YFMARAARLS GAEPDDEEYQ EFEEMLEHAE Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 99%.

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.

Specifications

• Antigen: VMP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VMP1
• Gene Alias: 3110098I04Rik; 4930579A11Rik; AI787464; EPG3; HSPC292; MIR21; mir-21a; NF-E2 induceble protein-2; NF-E2-inducible protein 2; ni-2; Protein ni-2; Tango5; TDC1; Tmem49; transmembrane protein 49; Vacuole membrane protein 1; VMP1; wu:fb05d08; wu:fb92g08; zgc:77153
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81671
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96GC9
• Gene Symbols: VMP1
• Immunogen: Recombinant protein corresponding to Human VMP1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only