Invitrogen™ VMP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA577784

Product Code. 16316504

Description

A 1:1,000 dilution of PA5-77784 was sufficient for detection of VMP1 in 15 μg of Human 293T Cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 46 kDa.

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.

Specifications

• Antigen: VMP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VMP1
• Gene Alias: 3110098I04Rik; 4930579A11Rik; AI787464; EPG3; HSPC292; MIR21; mir-21a; NF-E2 induceble protein-2; NF-E2-inducible protein 2; ni-2; Protein ni-2; Tango5; TDC1; Tmem49; transmembrane protein 49; Vacuole membrane protein 1; VMP1; wu:fb05d08; wu:fb92g08; zgc:77153
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81671
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q96GC9
• Gene Symbols: VMP1
• Immunogen: Synthetic peptide from the C-terminal of Human VMP1 (aa 391-402).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG