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Invitrogen™ VLK Polyclonal Antibody

Product Code. 12849022
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Quantity:
100 μg
Unit Size:
100µg
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12849022 100 μg 100µg
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Product Code. 12849022 Supplier Invitrogen™ Supplier No. PA520875

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human lung tissue lysate. PA5-20875 can be used with blocking peptide PEP-0989.

VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VLK
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PKDCC
Gene Accession No. Q504Y2, Q5RJI4
Gene Alias Adtk1; AI115348; AW548124; ESTM17; Extracellular tyrosine-protein kinase PKDCC; MAd1; Pkdcc; protein kinase domain containing, cytoplasmic; protein kinase domain containing, cytoplasmic homolog; protein kinase domain-containing protein, cytoplasmic; Protein kinase-like protein SgK493; RGD1311939; SGK493; Sugen kinase 493; vertebrate lonesome kinase; Vlk; X83346
Gene Symbols PKDCC
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the center of human VLK.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 106522, 313860, 91461
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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