vinculin Mouse, Clone: 7F9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9777-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15567676

Quantity Price
1 £ 61.7 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Clone 7F9
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.
Host Species Mouse
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Applications Western Blotting
Quantity 25μg
Isotype IgG1
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Species Reactivity Human, Mouse, Rat
Format Purified
Primary or Secondary Primary
Conjugate Unlabeled
Antigen vinculin

The monoclonal antibody 7F9 (VIIF9) recognizes human, mouse, rat, and avian vinculin and its alternatively spliced isoform, metavinculin. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin is involved in the anchoring of F-actin to the membrane and the regulation of E-cadherin expression. Vinculin binds to talin, paxillin, and alpha-actinin. Disregulation of vinculin alters cell adhesion, migration, and growth, which promotes cancer invasion and metastasis.