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Thermo Scientific™ Vinculin Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Vinculin Ab-1, Mouse Monoclonal Antibody.

Brand:  Thermo Scientific™ MS-1209-R1

Code : LD

Additional Details : Weight : 1.00000kg

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Product Code. 12689266

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance


Description

Description

Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and α actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.

Host Species: Mouse

Clone: VLN01

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Semi-purified vinculin

Molecular Weight: 130kDa (vinculin) and 150kDa (meta-vinculin)

Positive Control: HeLa cells, skin

Cellular Localization: Cell membrane and cytoplasmic Ab-1 is useful for studies of vinculin in platelet activation.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Vinculin Ab-1
Monoclonal
Unconjugated
Prediluted
Semi-purified vinculin
1mL
Cytoskeletal Protein
Primary
Human
ImmunofluorescenceþImmunohistochemistry (Paraffin)þImmunoprecipitationþWestern Blot
VLN01
Ready-to-use for IHC (UVLP)
Murine
IgG
RUO
Primary
Monoclonal
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