Invitrogen™ Human PHF15 Control Fragment Recombinant Protein

Product Code. 30210405

Brand: Invitrogen™ RP93570

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55275 (PA5-55275. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [UniProt]

Specifications

• Accession Number: Q9NQC1
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 23338
• Name: Human PHF15 Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 1200017K05Rik; AI480685; E3 ubiquitin-protein ligase Jade-2; jade family PHD finger 2; jade family PHD finger protein 2; JADE2; JADE-2; Kiaa0239; mKIAA0239; PHD finger protein 15; Phf15; protein Jade-2; protein Jade-2; E3 ubiquitin-protein ligase Jade-2; si:ch73-202g8.3
• Common Name: PHF15
• Gene Symbol: JADE2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ASVAADSDVQVLGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLA
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining