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  8. RU-SKI 43 hydrochloride, MedChemExpress

RU-SKI 43 hydrochloride, MedChemExpress

Product Code. 16409997
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Product Code. 16409997 Supplier Medchem Express Supplier No. HY18366A

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Description

MedChemExpress RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity.

RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity.

Specifications

Chemical Name or Material RU-SKI 43 hydrochloride
CAS 1782573-67-4
Color White
Purity Grade Notes Research
Molecular Formula C22H31ClN2O2S
Quantity 5 mg
Solubility Information DMSO : ≥ 51 mg/mL (120.56 mM) ∣H2O : 2.5 mg/mL (5.91 mM; Need ultrasonic)
SMILES [H]Cl.O=C(CNCC(C)CC)N1CCC2=C(C=CS2)C1COC3=CC=CC(C)=C3
Molecular Weight (g/mol) 423.01
Formula Weight 423.01
Percent Purity 98.54%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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