Invitrogen™ SETMAR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA543676

Product Code. 15576172

Description

Peptide sequence: FLQGKRFHNQ QDAENAFQEF VESQSTDFYA TGINQLISRW QKCVDCNGSY Sequence homology: Cow: 100%; Human: 100%.

SETMAR (SET domain and mariner transposase fusion gene) is a histone methyltransferase that methylates Lys-4 and Lys-36 of histone H3, creating specific tags for epigenetic transcriptional activation. It specifically mediates dimethylation of H3 Lys-36. SETMAR has sequence-specific DNA-binding activity, and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 transposable element. SETMAT has DNA nicking activity, and in vivo end-joining activity, and may mediate genomic integration of foreign DNA.

Specifications

• Antigen: SETMAR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SETMAR
• Gene Alias: 5830404F24Rik; epidermal tumor expressed transcript 2; Etet2; Histone-lysine N-methyltransferase; Histone-lysine N-methyltransferase SETMAR; Mar1; METNASE; SET domain and mariner transposase fusion gene; SET domain and mariner transposase fusion gene-containing protein; SET domain and mariner transposase fusion gene-containing protein homolog; SET domain and mariner transposase fusion protein; SET domain and mariner transposase fusion protein homolog; SET domain without mariner transposase fusion; SET domain without mariner transposase fusion protein; Setmar; Transposon Hsmar1 transposase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6419
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q53H47
• Gene Symbols: SETMAR
• Immunogen: Synthetic peptide directed towards the C-terminal of human SETMAR (aa 633-682).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG