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  5. STEMCELL Technologies Verteporfin

STEMCELL Technologies Verteporfin

Product Code. 17159981
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Quantity:
1 mg
5 mg
Unit Size:
1mg
5mg
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Product Code. 17159981

Brand: STEMCELL Technologies 1000261

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This item is not returnable. View return policy

Description

YAP1 inhibitor

  • Verteporfin is a benzoporphyrin derivative that inhibits autophagosome formation by directly targeting and modifying p62, a scaffold protein that targets polyubiquitinated proteins for degradation (Donohue et al.) Verteporfin also disrupts YAP-TEAD interactions by enhancing trypsin cleavage of YAP (EC50 = 100 nM; Brodowska et al.; Liu-Chittenden et al.)
  • Inhibits the growth, proliferation, and viability of human retinoblastoma cells (Brodowska et al.)
  • Inhibits self-renewal in cancer stem cells with high YAP1 and ALDH1 levels (Song et al.)

Specifications

CAS 129497-78-5
Synonym BPD-MA; CL 318,952
Quantity 1 mg
Molecular Formula C41H42N4O8
Purity ≥95%
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