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VER 155008, Tocris Bioscience™
Hsp70 inhibitor
£218.01 - £851.03
Chemical Identifiers
| CAS | 1134156-31-2 |
|---|---|
| Molecular Formula | C25H23Cl2N7O4 |
| Molecular Weight (g/mol) | 556.40 |
| MDL Number | MFCD18086892 |
| InChI Key | ZXGGCBQORXDVTE-UHFFFAOYNA-N |
| Synonym | 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis |
| PubChem CID | 25195348 |
| IUPAC Name | 4-({[5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile |
| SMILES | NC1=C2N=C(NCC3=CC(Cl)=C(Cl)C=C3)N(C3OC(COCC4=CC=C(C=C4)C#N)C(O)C3O)C2=NC=N1 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18023982
|
Tocris Bioscience
3803/10 |
10 mg |
£218.01
10mg |
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|
18094762
|
Tocris Bioscience
3803/50 |
50 mg |
£851.03
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Novel adenosine-derived inhibitor of Heat Shock Protein 70 (Hsp70) (IC50 = 0.5 μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78; displays selectivity against Hsp90β (IC50 >200 μM for Hsp90β).Chemical Identifiers
| 1134156-31-2 | |
| 556.40 | |
| ZXGGCBQORXDVTE-UHFFFAOYNA-N | |
| 25195348 | |
| NC1=C2N=C(NCC3=CC(Cl)=C(Cl)C=C3)N(C3OC(COCC4=CC=C(C=C4)C#N)C(O)C3O)C2=NC=N1 |
| C25H23Cl2N7O4 | |
| MFCD18086892 | |
| 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis | |
| 4-({[5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile |
Specifications
| 1134156-31-2 | |
| MFCD18086892 | |
| ZXGGCBQORXDVTE-UHFFFAOYNA-N | |
| 4-({[5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile | |
| 25195348 | |
| >98% |
| C25H23Cl2N7O4 | |
| 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis | |
| NC1=C2N=C(NCC3=CC(Cl)=C(Cl)C=C3)N(C3OC(COCC4=CC=C(C=C4)C#N)C(O)C3O)C2=NC=N1 | |
| 556.40 | |
| 556.4 | |
| VER 155008 |
Safety and Handling
Recommended Storage : Desiccate at Room Temperature