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Vemurafenib, MedChemExpress

Product Code. p-200096741
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Product Code. 16491026

Brand: Medchem Express HY12057

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Description

MedChemExpress Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively. Vemurafenib induces cell autophagy.

Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively. Vemurafenib induces cell autophagy.

Specifications

Chemical Name or Material Vemurafenib
CAS 918504-65-1
Color White
Purity Grade Notes Research
Molecular Formula C23H18ClF2N3O3S
Quantity 200 mg
Synonym PLX4032 RG7204 RO5185426
Solubility Information DMSO : 50 mg/mL (102.06 mM; Need ultrasonic)
SMILES FC1=CC=C(C(F)=C1C(C2=CNC3=NC=C(C=C32)C4=CC=C(C=C4)Cl)=O)NS(CCC)(=O)=O
Molecular Weight (g/mol) 489.92
Formula Weight 489.92
Percent Purity 98.04%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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