VEGF Receptor 3 Rat anti-Mouse, Clone: AFL4, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-5988-85

500UG:ANTI-MOUSE VEGF RECEPTOR 3 PURIFIED 500 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15227677

Quantity Price
1 £ 176.0 / 500µg
Estimated Shipment date
from Supplier 22-02-2017
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Description and Specification

Specification

Antigen VEGF Receptor 3
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias VEGFR3, VEGF R3, VEGF receptor 3, Flt-4, Flt4, vascular endothelial growth factor receptor 3
Host Species Rat
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2a
Quantity 500μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone AFL4
Concentration 0.5mg/mL
Conjugate Unlabeled

The AFL4 monoclonal antibody reacts with the mouse VEGF receptor-3, also known as Flt-4. This 195kDa molecule was identified as an endothelial-specific member of the receptor tyrosine kinase (RTK) family. During early embryogenesis all endothelial cells express VEGFR-3, while in the adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. However, VEGFR-3 expression is induced in the adult tissue upon tumor implementation suggesting an important role for this receptor in the tumor angiogenesis. VEGF-C and VEGF-D bind to and activate VEGFR-3. AFL4 is an antagonist mAb.