VDM 11 (inTocris Bioscience™olve 100), Tocris Bioscience™

Description

Potent, selective anandamide transport inhibitor (in water-soluble emulsion)

A potent and selective inhibitor of the anandamide membrane transporter (AMT), in water-soluble emulsion (for details see TocrisoveTM 100 ). IC50 values for inhibition of AMT are 4 - 11 mM. Displays negligible agonist activity at the hVR1 receptor and very weak action at CB1 and CB2 receptors. Ki values are > 5 - 10 mM at CB1 and CB2. Active in vivo.

VDM 11, pure oil dissolved in ethanol and Tocrisolve Control also available.