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Invitrogen™ VAV3 Polyclonal Antibody
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Product Code. 16537831
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Quantity:
100 μL
Unit Size:
100µL
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16537831 100 μL 100µL
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Product Code. 16537831 Supplier Invitrogen™ Supplier No. PA590428

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DNCGRVNSGE QGTLKLPEKR TNGLRRTPKQ VDPGLPKMQV IRNYSGTPPP ALHEGPPLQL QAGDTVELLK GDAHSLFWQG RNLASGEVGF FPSDAVKPCP CVPKPVDYSC QPWYAGAMER L; Positive Samples: Jurkat, Mouse brain, Mouse lung, Mouse spleen.

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VAV3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene VAV3
Gene Accession No. Q9R0C8, Q9UKW4
Gene Alias A530094I06Rik; AA986410; FLJ40431; guanine nucleotide exchange factor VAV3; Idd18.1; RGD1565941; vav 3 guanine nucleotide exchange factor; vav 3 oncogene; vav guanine nucleotide exchange factor 3; Vav3; VAV-3
Gene Symbols VAV3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 560-680 of human VAV3 (NP_0061044).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10451, 57257
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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