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Invitrogen™ VASN Polyclonal Antibody
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Product Code. 16541062
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Quantity:
100 μL
Unit Size:
100µL
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16541062 100 μL 100µL
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Product Code. 16541062 Supplier Invitrogen™ Supplier No. PA598236

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Description

Rabbit Polyclonal Antibody

VASN Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

The VASN gene encodes the protein vasorin, a type I transmembrane protein involved in cellular signaling, vascular development, and tissue repair. Vasorin is characterized by its expression in various tissues, including vascular endothelial cells and smooth muscle cells, where it functions to modulate cell proliferation and differentiation. It plays a significant role in the regulation of vascular remodeling and homeostasis by interacting with signaling molecules like transforming growth factor-beta (TGF-β), thereby influencing processes such as angiogenesis and wound healing. Vasorin is implicated in inhibiting TGF-β signaling pathways, which are crucial for maintaining vascular integrity and preventing excessive fibrosis during tissue repair. Dysregulation of VASN expression can contribute to pathological conditions, including cardiovascular diseases and cancer, where abnormal vascular remodeling and cell proliferation are evident. Research into vasorin continues to explore its functional mechanisms and potential therapeutic applications in diseases characterized by vascular dysregulation and tissue remodeling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VASN
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene VASN
Gene Accession No. Q6EMK4
Gene Alias 2610528G05Rik; Atia; Protein slit-like 2; Slitl2; Slit-like 2; UNQ314/PRO357/PRO1282; VASN; Vasorin
Gene Symbols VASN
Host Species Rabbit
Immunogen Peptide sequence from Human Vasorin protein (553-572AA).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114990
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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