Invitrogen™ VASH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551434

Product Code. 15759390

Description

Immunogen sequence: GALGMSRRED LMYKPPAFRT LSELVLDFEA AYGRCWHVLK KVKLGQSVSH DPHSVEQIEW KHSVLDVERL GRDDFRKELE RHARDMRLKI GKGTGPPSPT KDRKKDVSSP QRAQSSPHRR NSRSERRPSG DKKTSEPKAM PD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

VASH1 is a protein that possesses actin binding activity and metallocarboxypeptidase activity. It is involved in several processes including negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, and proteolysis. VASH1 acts upstream of or within processes such as negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, and negative regulation of lymphangiogenesis. It is located in the apical part of the cell, endoplasmic reticulum, and extracellular space. VASH1 is implicated in liver cirrhosis and portal hypertension, and is a biomarker of liver cirrhosis. Diseases associated with VASH1 include Portal Hypertension and Myasthenic Syndrome, Congenital, 14.

Specifications

• Antigen: VASH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VASH1
• Gene Alias: AI834978; D930046M13Rik; G630009D10Rik; KIAA1036; RGD1564082; TTCP 1; Tubulin carboxypeptidase 1; Tubulinyl-Tyr carboxypeptidase 1; Tyrosine carboxypeptidase 1; VASH; VASH1; vasohibin 1; vasohibin-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22846
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7L8A9
• Gene Symbols: VASH1
• Immunogen: Recombinant protein corresponding to Human VASH1. Recombinant protein control fragment (Product #RP-88864).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG