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  6. Invitrogen™ VAMP2 Recombinant Rabbit Monoclonal Antibody (K01_2U60)

Invitrogen™ VAMP2 Recombinant Rabbit Monoclonal Antibody (K01_2U60)
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Product Code. 30827830
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30827830 100 μL
30826638 50 μL
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Product Code. 30827830 Supplier Invitrogen™ Supplier No. MA564290

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Description

Rabbit Recombinant Monoclonal Antibody

VAMP2 Recombinant Monoclonal Antibody for Western Blot

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VAMP2
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_2U60
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene VAMP2
Gene Accession No. P63027, P63044, P63045
Gene Alias RATVAMPB; RATVAMPIR; SYB; SYB2; Syb-2; sybII; Synaptobrevin; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin II; synaptobrevin-2; vamp; Vamp2; VAMP-2; vesicle associated membrane protein 2; vesicle-associated membrane 2; Vesicle-associated membrane protein (synaptobrevin 2); vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)
Gene Symbols VAMP2
Host Species Rabbit
Immunogen A synthetic peptide of human VAMP2.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22318, 24803, 6844
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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