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  6. Invitrogen™ VAMP2 Recombinant Rabbit Monoclonal Antibody (K01_2J90)

Invitrogen™ VAMP2 Recombinant Rabbit Monoclonal Antibody (K01_2J90)
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Product Code. 30827135
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30827135 100 μL
30826601 50 μL
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Product Code. 30827135 Supplier Invitrogen™ Supplier No. MA563921

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Description

Rabbit Recombinant Monoclonal Antibody

VAMP2 Recombinant Monoclonal Antibody for ICC/IF, Western Blot

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VAMP2
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone K01_2J90
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene VAMP2
Gene Accession No. P63027, P63044, P63045
Gene Alias RATVAMPB; RATVAMPIR; SYB; SYB2; Syb-2; sybII; Synaptobrevin; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin II; synaptobrevin-2; vamp; Vamp2; VAMP-2; vesicle associated membrane protein 2; vesicle-associated membrane 2; Vesicle-associated membrane protein (synaptobrevin 2); vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)
Gene Symbols VAMP2
Host Species Rabbit
Immunogen A synthetic peptide of human VAMP2.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22318, 24803, 6844
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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