missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Valproic acid, MedChemExpress

Valproic acid, MedChemExpress

Product Code. 16496757
Encompass_Preferred
Click to view available options
Quantity:
1 g
5 g
25 g
Unit Size:
1g
25g
5g
This item is not returnable. View return policy

Product Code. 16496757

Brand: Medchem Express HY10585

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches.

Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches.

Specifications

Chemical Name or Material Valproic acid
Physical Form Liquid
CAS 99-66-1
Color Light Yellow
Quantity 5 g
Purity Grade Notes Research
Molecular Formula C8H16O2
For Use With (Application) Cancer-Kinase/protease
Synonym VPA 2-Propylpentanoic Acid
Solubility Information DMSO : 100 mg/mL (693.43 mM; Need ultrasonic) ∣H2O : 1 mg/mL (6.93 mM; Need ultrasonic and warming)
SMILES CCCC(CCC)C(O)=O
Molecular Weight (g/mol) 144.21
Formula Weight 144.21
Percent Purity 98.0%
Grade Research
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.