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Vactosertib Hydrochloride, MedChemExpress

Product Code. 16453897
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Product Code. 16453897

Brand: Medchem Express HY19928A

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Description

MedChemExpress Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect.

Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect.

Specifications

Chemical Name or Material Vactosertib Hydrochloride
CAS 1352610-25-3
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H19ClFN7
Quantity 50 mg
Synonym EW-7197 HydrochlorideTEW-7197 Hydrochloride
Solubility Information H2O : 50 mg/mL (114.71 mM; Need ultrasonic) ∣DMSO : 50 mg/mL (114.71 mM; Need ultrasonic)
SMILES CC1=CC=CC(C2=C(C3=CN4C(C=C3)=NC=N4)NC(CNC5=CC=CC=C5F)=N2)=N1.Cl
Molecular Weight (g/mol) 435.88
Formula Weight 435.88
Percent Purity 96.24%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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