Uzansertib phosphate, MedChemExpress

Product Code. 16490929

Brand: Medchem Express HY101870B

Description

MedChemExpress Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.

Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.

Especificaciones

• Chemical Name or Material: Uzansertib phosphate
• CAS: 2088852-47-3
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₆H₂₉F₃N₅O₇P
• Quantity: 1 mg
• Synonym: INCB053914 phosphate
• Solubility Information: DMSO : 5 mg/mL (8.18 mM; Need ultrasonic and warming)
• SMILES: O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O
• Molecular Weight (g/mol): 611.51
• Formula Weight: 611.51
• Percent Purity: 98.33%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only