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Uzansertib phosphate, MedChemExpress
Description
Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.
Specifications
Specifications
| Chemical Name or Material | Uzansertib phosphate |
| CAS | 2088852-47-3 |
| Color | Off-White |
| Purity Grade Notes | Research |
| Molecular Formula | C26H29F3N5O7P |
| Quantity | 1 mg |
| Synonym | INCB053914 phosphate |
| Solubility Information | DMSO : 5 mg/mL (8.18 mM; Need ultrasonic and warming) |
| SMILES | O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O |
| Molecular Weight (g/mol) | 611.51 |
| Show More |
Research purposes only
Product Title
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