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Uzansertib phosphate, MedChemExpress

Product Code. 16490929
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Product Code. 16490929 Supplier Medchem Express Supplier No. HY101870B

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MedChemExpress Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.

Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.

Specifications

Chemical Name or Material Uzansertib phosphate
CAS 2088852-47-3
Color Off-White
Purity Grade Notes Research
Molecular Formula C26H29F3N5O7P
Quantity 1 mg
Synonym INCB053914 phosphate
Solubility Information DMSO : 5 mg/mL (8.18 mM; Need ultrasonic and warming)
SMILES O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O
Molecular Weight (g/mol) 611.51
Formula Weight 611.51
Percent Purity 98.33%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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