PeproTech Uteroglobin Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
17854973	PeproTech 500-P330-50UG	50 μg
17815623	PeproTech 500-P330-100UG	100 μg
17865703	PeproTech 500-P330-1MG	1 mg

Description

AA Sequence of recombinant protein: MEICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Uteroglobin. Anti-Human Uteroglobin-specific antibody was purified by affinity chromatography employing an immobilized Human Uteroglobin matrix. Sandwich ELISA: To detect Human Uteroglobin by sandwich ELISA (using 100 μL/well), a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human Uteroglobin (500-P330BT) as a detection antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human Uteroglobin. Western Blot: To detect Human Uteroglobin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human Uteroglobin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.

Specifications

• Antigen: Uteroglobin
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P11684
• Gene ID (Entrez): 7356
• Immunogen: E.coli-derived Recombinant Human Uteroglobin.
• Purification Method: Antigen affinity chromatography
• Gene: SCGB1A1

• Concentration: 0.1-1.0 mg/mL
• Classification: Polyclonal
• Form: Lyophilized
• Regulatory Status: RUO
• Formulation: PBS with no preservative
• Gene Alias: Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; PCBB; PCB-binding protein; PCB-BP; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UG; Ugb; UP1; UP-1; Urinary protein 1; urine protein 1; uteroglobin; Uteroglobin (Clara cell secretory protein); Utg
• Gene Symbols: SCGB1A1
• Primary or Secondary: Primary
• Content And Storage: -20°C