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USP19 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16844335 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16844335 20 μL 20µL
16834335 150 μL 150µL
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Product Code. 16844335 Supplier Proteintech Supplier No. 257681AP20UL

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Description

Rabbit Polyclonal Antibody

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5′-region of the RUNX1 (AML1) gene fused to the 3′-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.

Specifications

Antigen USP19
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene USP19
Gene Accession No. O94966
Gene Alias Deubiquitinating enzyme 19, KIAA0891, Ubiquitin thiolesterase 19, USP19, ZMYND9
Gene Symbols USP19
Host Species Rabbit
Immunogen USP19 Fusion Protein Ag22646
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10869
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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