Uroplakin III Antibody - BSA Free, Novus Biologicals™

Rabbit Polyclonal Antibody

Brand:  Novus Biologicals NBP2-33126

Product Code. 18132504

Description

Uroplakin III Polyclonal specifically detects Uroplakin III in Human samples. It is validated for Western Blot.

Specifications

• Antigen: Uroplakin III
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with 0.05% Sodium Azide
• Gene Symbols: UPK3A
• Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin III (Uniprot: O75631)
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, CyTOF
• Concentration: 1.0 mg/mL
• Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, CyTOF-ready
• Gene Alias: MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a
• Host Species: Rabbit
• Molecular Weight of Antigen: 30 kDa
• Quantity: 0.1 mg
• Research Discipline: Cancer
• Gene ID (Entrez): 7380
• Target Species: Human
• Form: Purified

For Research Use Only