Invitrogen™ UPB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551450

Product Code. 15719410

Description

Immunogen sequence: GALSESLWPI EARNAAIANH CFTCAINRVG TEHFPNEFTS GDGKKAHQDF GYFYGSSYVA APDSSRTPGL SRSRDGLLVA KLDLNLCQQV NDVWNFKMTG RYEMYARELA EAVKSNYS Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.

UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

Specifications

• Antigen: UPB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UPB1
• Gene Alias: AI195023; Beta-alanine synthase; beta-ureidopropionase; beta-ureidopropionase 1; BUP1; BUP-1; N-carbamoyl-beta-alanine amidohydrolase; UPB1; ureidopropionase, beta; wu:fb69e03; zgc:64020
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51733
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UBR1
• Gene Symbols: UPB1
• Immunogen: Recombinant protein corresponding to Human UPB1. Recombinant protein control fragment (Product #RP-91381).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG