UNC5CL Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16841474	Proteintech 13322-1-AP-20UL	20 μL
16831474	Proteintech 13322-1-AP-150UL	150 μL

Description

UNC5CL is a membrane protein belonging to theUNC-5 family with a death domain and a ZU5 domain and is known to interact with p65/RELA and NFKB1. UNC5CL is known to interact with subunit p105 of NF-kappaB and transactivator p65 and is thus involved in inhibition of NF-kappaB activation and NF-kappaB-dependent transcription by inhibiting the binding of NF-kappaB to its target sequence (providing an alternative regulatory mechanism for NF-kappaB-mediated transcription). This regulatory protein sensitizes cells to apoptosis induced by TNF and TRAIL.

Specifications

• Antigen: UNC5CL
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human
• Gene Accession No.: Q6R653, Q8IV45
• Gene ID (Entrez): 222643, 76589
• Immunogen: UNC5CL Fusion Protein Ag3970
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: UNC5CL

• Concentration: 0.18 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Protein unc 5 homolog C like, UNC5C like protein, UNC5CL, ZUD
• Gene Symbols: Unc5cl
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody