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UNC2025, MedChemExpress

Product Code. 16417837
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Product Code. 16417837 Supplier Medchem Express Supplier No. HY12344

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Description

MedChemExpress UNC2025 is a potent, ATP-competitive and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 exhibits an excellent PK properties, and can be used for the investigation of acute leukemia.

UNC2025 is a potent, ATP-competitive and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM

Specifications

Chemical Name or Material UNC2025
CAS 1429881-91-3
Color White
Purity Grade Notes Research
Molecular Formula C28H40N6O
Quantity 5 mg
Solubility Information DMSO : 33.33 mg/mL (69.92 mM; Need ultrasonic and warming)
SMILES CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C53)C=C2)CC1
Molecular Weight (g/mol) 476.66
Formula Weight 476.66
Percent Purity 96.86%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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