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UNC0321, MedChemExpress

Product Code. p-200100895
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16494288 10 mg 10mg
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Description

MedChemExpress UNC0321 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 63 pM and with assay-dependent IC50 values of 6-9 nM. UNC0321 also inhibits GLP with assay-dependent IC50 values of 15-23 nM. UNC0321 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E.

UNC0321 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 63 pM and with assay-dependent IC50 values of 6-9 nM. UNC0321 also inhibits GLP with assay-dependent IC50 values of 15-23 nM. UNC0321 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E.

Specifications

Chemical Name or Material UNC0321
CAS 1238673-32-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C27H45N7O3
Quantity 10 mg
Solubility Information DMSO : ≥ 31 mg/mL (60.11 mM)
SMILES CN1CCC(NC2=C3C=C(OC)C(OCCOCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1
Molecular Weight (g/mol) 515.69
Formula Weight 515.69
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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