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UMI-77, MedChemExpress

Product Code. 16463567
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Quantity:
5 mg
10 mg
50 mg
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10mg
50mg
5mg
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Product Code. 16463567

Brand: Medchem Express HY18628

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MedChemExpress UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.

UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.

Specifications

Chemical Name or Material UMI-77
CAS 518303-20-3
Color White
Purity Grade Notes Research
Molecular Formula C18H14BrNO5S2
Quantity 50 mg
Solubility Information DMSO : ≥ 28 mg/mL (59.79 mM)
SMILES O=C(O)CSC1=CC(NS(=O)(C2=CC=C(Br)C=C2)=O)=C3C=CC=CC3=C1O
Molecular Weight (g/mol) 468.34
Formula Weight 468.34
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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