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UMI-77, MedChemExpress
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
Description
UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
Specifications
Specifications
| Chemical Name or Material | UMI-77 |
| CAS | 518303-20-3 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C18H14BrNO5S2 |
| Quantity | 50 mg |
| Solubility Information | DMSO : ≥ 28 mg/mL (59.79 mM) |
| SMILES | O=C(O)CSC1=CC(NS(=O)(C2=CC=C(Br)C=C2)=O)=C3C=CC=CC3=C1O |
| Molecular Weight (g/mol) | 468.34 |
| Formula Weight | 468.34 |
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Research purposes only
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