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Invitrogen™ ULK3 Polyclonal Antibody

Description
Antibody detects endogenous levels of total ULK3.
ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins.
Specifications
Specifications
| Antigen | ULK3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | ULK3 |
| Gene Accession No. | Q3U3Q1, Q6PHR2 |
| Gene Alias | 1200015E14Rik; DKFZP434C131; EC:2.7.11.1; FLJ90566; Serine/threonine-protein kinase ULK3; ULK3; unc-51 like kinase 3; unc-51-like kinase 3 |
| Gene Symbols | ULK3 |
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Product Title
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