Invitrogen™ ULK2 Monoclonal Antibody (2H4B8)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA531949

Product Code. 16385374

Description

MA5-31949 has been tested in indirect ELISA.

ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.

Specifications

• Antigen: ULK2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q8IYT8
• Gene Symbols: ULK2
• Immunogen: Purified recombinant fragment of human ULK2 (AA: 1-155) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 2H4B8
• Conjugate: Unconjugated
• Gene: ULK2
• Gene Alias: A830085I22Rik; ATG1B; AU015340; EC:2.7.11.1; KIAA0623; mKIAA0623; serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase Unc51.2; ULK2; unc-51 like autophagy activating kinase 2; unc-51 like kinase 2; Unc51.2; unc-51-like kinase 2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 9706
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid