Invitrogen™ UGT2B7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595854

Product Code. 16588691

Description

Immunogen sequence: KVLVWAAEYS HWMNIKTILD ELIQRGHEVT VLASSASILF DPNNSSALKI EIYPTSLTKT ELENFIMQQI KRWSDLPKDT FWLYFSQVQE IMSIFGDITR KFCKDVVSNK KFMKKVQESR FDVIFADAIF PCSELLAELF NIPFVYSLSF SPGYTFEKHS GGFIFPPSYV PVVMSELTDQ MTFMERVKNM IYVLYFDFWF EIFDMKKWDQ FYSEVLGRPT TLSETMGKAD VWLIRNSWNF QFPYPLLPNV DFVGGLHCKP AKPLPKEMED FVQSSGENGV VVFSLGSMVS NMTEERANVI ASALAQIPQK VLWRFDGNKP DTLGLNT; Positive Samples: HepG2, 293T; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein.

The UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.

Specifications

• Antigen: UGT2B7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UGT2B7
• Gene Alias: 3,4-catechol estrogen specific; 3,4-catechol estrogen-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glucuronosyltransferase 2B7; UDP glucuronosyltransferase family 2 member B7; UDP-glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B8; UDP-glucuronosyltransferase 2B9; UDP-glucuronyltransferase, family 2, beta-7; UDPGT; UDPGT 2B7; UDPGT 2B8; UDPGT 2B9; UDPGT2B7; UDPGTh 2; UDPGTH2; UDPGTh-2; Ugt2b7; Ugt2b8; UGT2B9; UGT2B-RH4; UGTB2B9
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286989, 7364
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P16662, Q62789
• Gene Symbols: UGT2B7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-351 of human UGT2B7 (NP_0010652).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG