Invitrogen™ UCP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584822

Product Code. 16311775

Description

Immunogen sequence: MQGEAALARL GDGARESAPY RGMVRTALGI IEEEGFL Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 89%.

UCP4 is a 323 amino acid mitochondrial uncoupling protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats. UCP4 is a mitochondrial transport carrier that facilitates the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. It reduces the mitochondrial membrane potential in mammalian cells and is involved in thermoregulatory heat production. UCP4 creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis resulting in dissipation of energy in the form of heat. UCP4 is usually found in adult and fetal brain, with low levels in spinal chord, corpus callosum and substantia nigra.

Specifications

• Antigen: UCP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC25A27
• Gene Alias: 3632410G24Rik; 9430092A03Rik; D530043E16Rik; Mitochondrial uncoupling protein 4; slc25a27; Solute carrier family 25 member 27; solute carrier family 25, member 27; UCP 4; ucp4; uncoupling protein; uncoupling protein 4; uncoupling protein UCP-4; UNQ772/PRO1566; zgc:63899
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9481
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95847
• Gene Symbols: SLC25A27
• Immunogen: Recombinant protein corresponding to Human SLC25A27. Recombinant protein control fragment (Product #RP-107708).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG