Invitrogen™ UCP3 Recombinant Rabbit Monoclonal Antibody (10I0J9)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA555374

Product Code. 30132259

Description

Immunogen Sequence: YDILKEKLLD YHLLTDNFPC HFVSAFGAGF CATVVASPVD VVKTRYMNSP PGQYFSPLDC MIKMVAQEGP TAFYKGFTPS FLRLGSWNVV MFVTYEQLKR A.

The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.

Specifications

• Antigen: UCP3
• Classification: Recombinant Monoclonal
• Concentration: 1.25 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P56501
• Gene Symbols: Ucp3
• Immunogen: Synthetic peptide.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 10I0J9
• Conjugate: Unconjugated
• Gene: Ucp3
• Gene Alias: AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 22229
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid