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Invitrogen™ UCMA Polyclonal Antibody

Product Code. 12858912
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Quantity:
100 μg
Unit Size:
100µg
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12858912 100 μg 100µg
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Product Code. 12858912 Supplier Invitrogen™ Supplier No. PA520768

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Description

Rabbit Polyclonal Antibody

A suggested positive control is SW1353 cell lysate. PA5-20768 can be used with blocking peptide PEP-0882.

UCMA is a gene that encodes for a protein that is specific to chondrocytes and highly charged. This protein is expressed abundantly in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the protein has been associated with osteoarthritis in humans. Alternative splicing of the gene results in multiple transcript variants that encode different isoforms. UCMA is also associated with diseases such as Osteoarthritis and Poland Syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UCMA
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene UCMA
Gene Accession No. Q14BU0, Q8WVF2
Gene Alias 1110017I16Rik; AW121955; C10orf49; Gla-rich protein; GRP; GRP/UCMA; RGD1308977; Ucma; ucma {ECO:0000250; Ucma-C; UniProtKB:Q14BU0}; Unique cartilage matrix-associated protein; unique cartilage matrix-associated protein {ECO:0000250; Unique cartilage matrix-associated protein C-terminal fragment; upper zone of growth plate and cartilage matrix associated; upper zone of growth plate and cartilage matrix associated protein
Gene Symbols UCMA
Host Species Rabbit
Immunogen A 16 amino acid peptide near the carboxy terminus of human UCMA.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221044, 68527
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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