UCHL3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA533098

Product Code. 13434769

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Dog, Elephant, Opossum, Turkey, Chicken, Lizard (100%); Orangutan, Monkey, Bovine, Horse, Rabbit, Pig, Salmon (94%); Pufferfish, Zebrafish, Stickleback, Water flea (89%); Xenopus (83%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.

Specifications

• Antigen: UCHL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UCHL3
• Gene Alias: RGD1561196; testicular tissue protein Li 221; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin C-terminal hydrolase L3; Ubiquitin thioesterase L3; ubiquitin thiolesterase; UCHL3; UCH-L3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 395626, 498560, 50933, 7347
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P15374, Q91Y78, Q9JKB1
• Gene Symbols: UCHL3
• Immunogen: Synthetic 18 amino acid peptide from internal region of human UCHL3.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Chicken, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG