UCH-L1/PGP9.5 Antibody (31A3), Novus Biologicals™

Mouse Monoclonal Antibody has been used in 13 publications

Product Code	Brand	Quantity
18527721	Novus Biologicals NB600-1160-20ug	20 μg

Description

UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human, Mouse, Rat, Porcine, Bovine, Zebrafish samples. It is validated for Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: UCH-L1/PGP9.5
• Concentration: 0.2 mg/ml
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cellular Markers, Neuronal Cell Markers, Neuroscience, Neurotransmission
• Gene Accession No.: P09936
• Gene ID (Entrez): 7345
• Immunogen: UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C.
• Molecular Weight of Antigen: 25 kDa

• Clone: 31A3
• Dilution: Western Blot 1-2 μg/mL, Simple Western 10 μg/mL, Flow Cytometry 1-2 μg/million cells, Immunohistochemistry 1-2 μg/mL, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunohistochemistry-Paraffin 1-2 μg/mL, Immunohistochemistry-Frozen 1-2 μg/mL
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Alias: EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
• Gene Symbols: UCHL1
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

For Research Use Only