Ubiquitin Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA126088

Product Code. 11531562

Description

PA1-26088 detects Ubiquitin from human and mouse samples.

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.

Specifications

• Antigen: Ubiquitin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBB
• Gene Alias: 0610006J14Rik; 1810034D23Rik; 2700054O04Rik; 40S ribosomal protein S27a; 40S ribosomal protein S27-like; 40S ribosomal protein S27-like protein; AI194771; AL033289; CEP80; CG5271; CG5271-PA; Chap1; Dmel\CG5271; Dmel_CG5271; Dub80; epididymis luminal protein 112; epididymis secretory protein Li 50; HEL112; HEL-S-50; hm:zeh0386; HMG20; hPLIC-2; HRIHFB2157; HUBCEP52; ik:tdsubc_1f2; l(2)04820; l(2)31Ei; LOC100912032; LOC101747587; male female sterile 31; mfs(2)31; mfs(2)48; mfs48; OTTHUMP00000200786; OTTHUMP00000201692; PLIC-2; polyubiquitin; polyubiquitin B; polyubiquitin C; poly-ubiquitin precursor; polyubiquitin-B; Polyubiquitin-C; polyubiquitin-C-like; RE44350p; ribosomal protein S27; ribosomal protein S27 like; ribosomal protein S27A; ribosomal protein S27a L homeolog; ribosomal protein S27a S homeolog; ribosomal protein S27-like; ribosomal protein S27-like protein; RPL40; RpS27; Rps27a; rps27a.L; rps27a.S; RpS27A-PA; RPS27L; S27A; similar to polyubiquitin; similar to ubiquitin-S27a f
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 22186, 22187, 22190, 281370, 286839, 444874, 51065, 614220, 615199, 6233, 67941, 7311, 7314, 7316, 78294
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.2
• Gene Accession No.: P0CG47, P0CG48, P0CG49, P0CG50, P0CG53, P0CH28, P62979, P62983, P62984, P62987, P62992, P63048, Q3T0B7, Q6ZWY3, Q71UM5
• Gene Symbols: RPS27A, RPS27L, UBA52, UBB, UBC
• Immunogen: Full length native Ubiquitin protein purified from bovine red blood cells.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Human, Mouse
• Product Type: Antibody
• Isotype: IgG