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Invitrogen™ UBF-1 Polyclonal Antibody
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Product Code. 16399204
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Quantity:
100 μL
Unit Size:
100µL
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16399204 100 μL 100µL
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Product Code. 16399204 Supplier Invitrogen™ Supplier No. PA582245

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WKLLSQKEKD AYHKKCDQKK KDYEVELLRF LESLPEEEQQ RVLGEEKMLN INKKQATSPA SKKPAQEGGK GGSEKPKRPV SAMFIFSEEK RRQLQEERPE LSESELTRLL ARMWNDLSEK KK Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 98%.

UBF-1 encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
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Specifications

Antigen UBF-1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene UBTF
Gene Accession No. P17480, P25976
Gene Alias 90-kDa nucleolus organizer region autoantigen; A930005G04Rik; Autoantigen NOR-90; NOR90; NOR-90; Nucleolar transcription factor 1; Tcfubf; transcription factor UBF; UBF; UBF1; UBF-1; UBF2; Ubtf; upstream binding transcription factor, RNA polymerase I; upstream-binding factor 1
Gene Symbols UBTF
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human UBTF. Recombinant protein control fragment (Product #RP-89322).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21429, 7343
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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