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Invitrogen™ UBE4A Recombinant Rabbit Monoclonal Antibody (24GB1785)
Description
UBE4A Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
Specifications
Specifications
| Antigen | UBE4A |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 24GB1785 |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Ube4a |
| Gene Accession No. | E9Q735, Q14139, Q6P7A2 |
| Gene Alias | 4732444G18Rik; 9930123J21Rik; Ab2-232; E4; KIAA0126; RING-type E3 ubiquitin transferase E4 A; UBE4A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; UBOX2; UFD2; UFD2b |
| Gene Symbols | Ube4a |
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