Invitrogen™ UBE2D2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552024

Product Code. 15719980

Description

Immunogen sequence: LTDLQRDPPA QCSAGPVGDD LFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTKIYHPNIN SNGSICLDIL RS Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Specifications

• Antigen: UBE2D2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE2D2
• Gene Alias: (E3-independent) E2 ubiquitin-conjugating enzyme D2; 1500034D03Rik; E2 ubiquitin conjugating enzyme UbcH5B; E2 ubiquitin-conjugating enzyme D2; E2(17)KB 2; E2(17)KB2; E217kB; p53-regulated ubiquitin-conjugating enzyme 1; PUBC1; similar to ubiquitin-conjugating enzyme E2D 2; Ubc2e; ubc2e ubiquitin conjugating enzyme; ubc4; UBC4/5; UBC5B; UBCH4; UBCH5B; ube2d2; Ube2d2a; Ubiquitin carrier protein D2; ubiquitin conjugating enzyme 2e; ubiquitin conjugating enzyme E2 D2; ubiquitin conjugating enzyme E2D; ubiquitin conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2(17)KB 2; ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 2A; ubiquitin-protein ligase D2; Unknown (protein for MGC:138112); zgc:55886; zgc:55886 protein; zgc:77149; zmp:0000000618
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56550, 641452, 7322
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P62837, P62838, P62839
• Gene Symbols: UBE2D2, Ube2d2a
• Immunogen: Recombinant protein corresponding to Human UBE2D4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG