Invitrogen™ UBE2C Recombinant Rabbit Monoclonal Antibody (SAIC-41C-6)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA551837

Product Code. 30089523

Description

Recognises human UBE2C.

This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Specifications

• Antigen: UBE2C
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: O00762
• Gene Symbols: UBE2C
• Immunogen: Peptide LSLEFPSGYPYNAPTVK derived from the Ubiquitin-conjugating enzyme E2C, conjugated to KLH (aa 81-97).
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry, Mass Spectrometry
• Clone: SAIC-41C-6
• Conjugate: Unconjugated
• Gene: UBE2C
• Gene Alias: (E3-independent) E2 ubiquitin-conjugating enzyme C; 1110015A16Rik; cyclin-selective ubiquitin carrier protein; D2Ertd695e; dJ447F3.2; E2 ubiquitin-conjugating enzyme C; mitotic-specific ubiquitin-conjugating enzyme; RP3-447F3.1; ubcH10; UBE2C; Ubiquitin carrier protein C; ubiquitin conjugating enzyme E2 C; ubiquitin conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; ubiquitin-conjugating enzyme E2C; ubiquitin-protein ligase C
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11065
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid