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  6. UBASH3A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

UBASH3A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7207132 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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Product Code. Quantity unitSize
16875184 20 μL 20µL
16865184 150 μL 150µL
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Product Code. 16875184 Supplier Proteintech Supplier No. 158231AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody is UBASH3A-specific.

TULA (T cell ubiquitin ligand, UBASH3A, ubiquitin associated and SH3 domain containing A), STS-2 or CLIP4, is a 661 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one SH3 domain and one UBA domain. Expressed at high levels in thymus, bone marrow, spleen and peripheral blood leukocytes, TULA exists as either a homodimer or a homo-oligomer that interferes with the degradation of receptor-type tyrosine kinases and promotes the accumulation of activated receptors on the cell surface. Additionally, TULA is part of an EGFR- and Cbl-containing complex that interacts with ubiquitinated proteins. The gene encoding TULA, which maps to human chromosome 21, may be involved in the pathogenesis of type I diabetes. Multiple isoforms of TULA are produced due to alternative splicing events.

Specifications

Antigen UBASH3A
Applications Immunoprecipitation, Immunocytochemistry, Western Blot, Immunofluorescence
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene UBASH3A
Gene Accession No. P57075, Q3V3E1
Gene Alias Cbl interacting protein 4, CLIP4, STS 2, STS2, T cell ubiquitin ligand, TULA, UBASH3A
Gene Symbols Ubash3a
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 309666, 328795, 53347
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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