Invitrogen™ TYRP1 Recombinant Mouse Monoclonal Antibody (TA99)

Mouse Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA551827

Product Code. 30088189

Description

Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin production and determine the shape of melanosomes, which are the structures in melanocytes where melanin is produced.

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

Specifications

• Antigen: TYRP1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P17643
• Gene Symbols: TYRP1
• Immunogen: 70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: TA99
• Conjugate: Unconjugated
• Gene: TYRP1
• Gene Alias: 5,6-dihydroxyindole-2-carboxylic acid oxidase; B; b-PROTEIN; brown; Brown locus protein; CAS2; Catalase B; CATB; DHICA oxidase; glycoprotein 75; GP75; iris stromal atrophy; isa; melanogenic enzyme; melanoma antigen gp75; MGC120175; MGC149362; OCA3; RP11-3L8.1; TRP; TRP1; TRP-1; truncated Tyrp1; TRY1; TRY4; TRYP1; tyrosinase related protein 1; tyrosinase-related protein 1; tyrosinase-related protein 1 precursor; tyrosine phosphatase 1, same as B (Brown); TYRP; Tyrp1; Tyrp-1; TYRRP
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7306
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid