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Invitrogen™ TYROBP Polyclonal Antibody

Product Code. 11586072
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Quantity:
100 μg
Unit Size:
100µg
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11586072 100 μg 100µg
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Product Code. 11586072 Supplier Invitrogen™ Supplier No. PA112701

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Description

Rabbit Polyclonal Antibody

A suggested positive control for this product is NKp44 positive cells.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYROBP
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene TYROBP
Gene Accession No. O43914, O54885
Gene Alias DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp
Gene Symbols TYROBP
Host Species Rabbit
Immunogen Recombinant DAP12 protein.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22177, 7305
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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