Invitrogen™ TWIST2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599393

Product Code. 16633645

Description

Antibody detects endogenous levels of total Twist2.

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Specifications

• Antigen: TWIST2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TWIST2
• Gene Alias: AMS; BBRSAY; bHLHa39; Class A basic helix-loop-helix protein 39; dermis expressed 1; dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; SETLSS; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 2; twist homolog 2; TWIST2; twist-related bHLH protein Dermo1; twist-related protein 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117581, 13345, 59327
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P97831, Q8WVJ9, Q9D030
• Gene Symbols: TWIST2
• Immunogen: A synthesized peptide derived from human TWIST2(Accession Q8WVJ9), corresponding to amino acid residues S10-S60.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG