missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Melford Tunicamycin

Melford Tunicamycin

Product Code. 30018834
Change view
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
30018834 50 mg 50mg
30018833 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 30018834 Supplier Melford Supplier No. T225000.05

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Tunicamycin is a nucleoside antibiotic that inhibits the biosynthesis of N-linked glycoproteins.

Tunicamycin is a nucleoside antibiotic that inhibits the biosynthesis of N-linked glycoproteins. It inhibits the formation of N-glycosidic linkages during the early steps of protein glycosylation. Also, it interferes with the transfer of N-acetylglucosamine-1-phosphate to dolichol phosphate, a crucial step in the synthesis of lipid-linked oligosaccharides. As a result, the glycosylation process in the endoplasmic reticulum is disrupted.

Widely used as a tool in cell biology and biochemistry to study protein glycosylation. It helps researchers investigate the effects of impaired glycosylation on cellular processes. This antibiotic induces endoplasmic reticulum (ER) stress by disrupting protein folding and glycosylation in the ER. This property is utilized in studies focused on understanding ER stress responses and unfolded protein response pathways.

Tunicamycin is a valuable tool for investigating the role of protein glycosylation in cellular functions and for inducing ER stress for studies related to unfolded protein responses.

Specifications

Chemical Name or Material Tunicamycin
CAS 11089-65-9
Quantity 50 mg
Molecular Formula C39H64N4O16
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.