Invitrogen™ TTLL12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA576352

Product Code. 15972875

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.

Specifications

• Antigen: TTLL12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TTLL12
• Gene Alias: BC055368; D430005B17; dJ526I14.2; Inactive tubulin--tyrosine ligase-like protein 12; KIAA0153; RGD1305319; TTL domain protein; ttll12; tubulin tyrosine ligase like 12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; tubulin--tyrosine ligase-like protein 12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 223723, 23170, 300105
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14166, Q3UDE2
• Gene Symbols: TTLL12
• Immunogen: Recombinant protein of human TTLL12.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG